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Acarbose

Combinations ; - see below

Acarbose Brands

Brand Name Manufacturer Name Distributor Drug Strength Packaging Formulation Formulation Strength Price
Glucobay Bayer Schering Pharma Bayer East Africa Ltd. 50mg 90 Tablet per tablet KES 2,031.93
Glucobay Bayer Schering Pharma Bayer East Africa Ltd. 100mg 90 Tablet per tablet KES 2,924.31
test4 Aci Limited C.Mehta & Co Ltd. 0.02% 52gm Diagnostic KES 330

Acarbose More info
Mode Of Action

It inhibits intestinal alpha-glucosidases hence delaying the digestion and absorption of starch and sucrose.

Drug Indication Diabetes mellitus inadequately controlled by diet or by diet with oral hypoglycaemic agents.
Precautions Monitor serum hepatic transaminase in patients on 200mg/day for the first six months; may enhance hypoglycaemic effect of insulin and sulphonylureas. Due to its MOA, hypoglycaemic episodes should be treated with oral glucose not sucrose.
Contra-Indications Under 18 years; pregnancy; states that deteriorate due to increased gas formation (e.g. intestinal ulcer and hernia); breastfeeding; severe renal and hepatic impairment; inflammatory bowel disease; intestinal obstruction; colon ulceration; and history of abdominal surgery.
Side Effects Flatulence and bowel sounds; diarrhoea; abdominal distension; abdominal pain (less common); hypersensitivity reactions; jaundice; and hepatitis.
Dosage Initially 25mg TID at the start of each main meal. Dosage may be adjusted at 4-8 weeks intervals, first to 50mg TID then, if required, to 100mg TID.
Special Information It is an oligosaccharide obtained from fermentation processes of the microorganism Actinoplanes utahensis
Pregnancy Category Category B3
Pregnancy Category Description Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals show evidence of an increased occurrence of foetal damage, the significance of which is uncertain in human
Drug Category DRUGS AFFECTING NUTRITION AND METABOLISM
Drug Sub-Category Other medicines for treatment of diabetes